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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2164af2fe100163df646410050db8e4237da2cdb7ea43837c281bdc9fe646fa8' 
  AND token = 'p7Gx4WF+37q9/Bu48O6KeQyAxk3nA05l31LWcvEsvbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}