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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b831f998b6cf236ceba16b447eb5f124cd9dad2254ea8c64e8525a6358b5a60' 
  AND token = 'ruvb/Lf3sHQ0F63XTDvWWq3v2iIDxOPI5d9rI30DWwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}