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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc0c073a3ac69b192242800981b3cf767445a7d0a2467bb9a905032aa7d5b69' 
  AND token = 'ilS5Mo7MHXjME3TjFBD9hNeATwKCsR7O7GB7/yMGtrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}