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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de25f971100ec58feddd2f6ea23dbd4bd6f3c857ace034d53561749fc9200e8' 
  AND token = 'JTYfSDS9eSpcjfjS6ZaLNRtIgc+c0o8o2dE2uaLWbDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}