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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403d648fcfb8ba69edb2b14c41ac72d7a225d802e2bdc564f7c86b563114290c' 
  AND token = 'ZcokHg9qXDwhSFUeTxjF0W8wm7Ck4LLBWp0TZa69VX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}