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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd31791b5e88648e13c647646ed14a98b780b85bd8038f4da59227f7c433c20b1' 
  AND token = 'RKFIIQS5Emq3MWaOv/W017RNtS3Uqb+uNl0y50eTN8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}