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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e67df1faf058eb350b6e6f4dff736400640f94a8b1f9b930422e142cec0f849' 
  AND token = 'Seq25WSDixnpeBe5JGRjVjE810KZ4Zo/rowiqQL7d0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}