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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab57a2cb98c1662f2f89cf807e4a9cadc2bb0e139dca15183f270a76492015f' 
  AND token = 'oYQj8hZk/6a9VPVUdx5m2whGbmZjcOO0vkrdTwUZYmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}