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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dde6511b5af71d222e4b796cd8b2a00741259a62d36a0d91af264ce39901a7' 
  AND token = 'k2rHt3LQd1cCiyPBNV5gYGex4XbF5rO9vW/3cRzN/Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}