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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9bae39c67adbc2fda3704b263eaa71c003c416a5761e095b884ebe40d7d997' 
  AND token = 'HUOOXhyJ9eCDXJkFx1eYqUOhAr0GcXnA/pF4JgBf66I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}