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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d08f629bf9c2864cfea9e717b451e1417946e1afa37573fd62bb645498a6133' 
  AND token = 'jmyBBLLa3bt3ZyyuJZQ0CPmIsQl19mBuvsjh61XuIi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}