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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1ddc507b5828595bce3025b729b55178fe9374d4d49600ac2789532646f4b2' 
  AND token = 'T0+t5gjOydNuWdHVBrKIW+xkYFQaHDXSMhrmfOhgL54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}