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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5615fe03ac521adccf9ea74e6e969eda6d64d7e89168e14b324cbb3c49f0edc' 
  AND token = '2yw38ZLMQYQp8F2Cjn1BmH2Hh0DZeWAy1a3/QsSPzsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}