SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddd57d1d6253187247ba4a034095f95e59378c1c7ead289fe7022852cad41f8e' 
  AND token = 'Reop6DFGko7yEI+kmQtt9tGr0rLjZbf7M6p5veo0poU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}