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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee146ac48109a8cfcec5fd0903ba4eab1be7e48e5a28ad7263c12179a21495b6' 
  AND token = '5lGsFw7Vy8uipJRcxJ4bUl3oOzLJUw1NCWzj+n7wS3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}