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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9c2c95caf336c5a85c7e77b38c24bae3111267d5d6cf8e6412ffd63d875929' 
  AND token = 'tT6fqt3XzcLgEN+E4sMj6Q+FUcJNjYy4kulrpmd0D74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}