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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b9a4bfeadc69c4ad7651399ba92052be5a908f006962d26dec96e602fcbd3fc' 
  AND token = 'juVtmxaXwUceKQHoRoRkpbjaVhSEspZvt1+bpu6efYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}