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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750059b933c9bea409ea6e5f4f500a95dcc1ac64d8ccee02d1a7ad0da979b125' 
  AND token = 'Rixzk8t/qtOWwl3cNikPl3no/u4zT6tSI84OOjklE7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}