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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6381b6f7c714f4f16d0905781cade353dda3d78a7f41788efb3bb7ba833e6b52' 
  AND token = 'zIz3p/xPOluCg1LSW/9QcjEli+3bAO0YXbCOV44m1x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}