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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74f19e4a8b10670d0118a54c5e335d4804515162a09acfe12e71ce30635a948' 
  AND token = 'gTEJUpaAC2Molaq/MUlTzQyhV+Yqoged30Gy0Ng+orM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}