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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d0109bc74efa1120f48dc7292838da80096a4a59126a85d6c3be84bb6877ad' 
  AND token = 'VGaitjlBHk6NYRpZlKCHUyrcLAPYyWJ+0sw+eaMEX30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}