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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b80488923a4ea5b0bccd401d12203755633fa4f34e604c1564fa1887b1b468e' 
  AND token = 'OmTkSpcR+vl0ghhw6veQFHuTJks6sZFxdYJStcE9l58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}