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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910e216b110359ec9d26ac67b8955e817b409da8730e1431d85b25e3ce1d9226' 
  AND token = 'QBApoo8On84VJuJ+pfQ/eVyrtEeqG1qfgfpXjOZIDjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}