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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f89a06e99b0a4494b3fb7ee7b07cc924e90245e75add22ebb4ec0074809ab9' 
  AND token = 'DbaM8aHKhKc480HZLEZVft1x+lPfgPyBJF8J8EHo5BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}