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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a068242c52c697f54e81e9388b430a49a28ca09bfc5e353327d0a2e09808b6e2' 
  AND token = 'OP71qzLMEo5W39DvAes6nrGYkDwoSees/0X6MIETsIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}