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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5baab58d13bb4a8babad68308c3e978522c0298ea40d50a9ac00ab3fd783d206' 
  AND token = 'AvXTIgLjYiv+rT9PpRdfYkYBBHhXgrOPtaO0b6gKuOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}