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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e61cdeaad8f519ed39967fc6ee4f595c96e10818a7b40e9bd2b6c41d1bead4' 
  AND token = 'ShF3bLt/RTkz9EnbwYm3BPCL3ATEHgEsY0V9Bgf35cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}