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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9422be226e2a623a7356677a211950be66d3a1800a00171230b13ccae5d474' 
  AND token = 'lQMnlPRkZu9TNc8oDtTx4rMa6Cdd26LQ2Orayx4gU44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}