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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396194364bf14189b8680bcd2744c14f32e7ce45a09e2380392c94527e1243e5' 
  AND token = 'PMTzBxyd7pTs98BNkzV+UV76dK+dksNsNeUzI0IL/+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}