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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daa741858f0aa4d391c7b1c888b76842bb2d9cc627465524528e365e4e355cec' 
  AND token = 'CTXN6oAD3ZhE0hAsSwh0fSFbEw27/aCMxrZI7Ee4NAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}