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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0fe21b24efc2cb7231c017cc235011fb774f2fed55f6083f70e1911583a6b02' 
  AND token = 'wXBBpB01JKDZK91IgqhOLX+gqC1YPwNeeqUqmWK6h3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}