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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ddb711bf1d06295db46b6696293d5e8b412c3f0392889da9c1af5aa2020fdd' 
  AND token = 'CnycZPqBrw3AzOtG9IaIkKaalr4Uznb4ITo3IV6oUP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}