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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4640e26ead958699fdec0a301a4f571442d1dd49e497d044c635b17978c24bbe' 
  AND token = 'KcyzbdFX3EsPJyiDvZGqeWj6vK2V1y9pTgvLQX4MMqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}