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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93d721db50a8eae60e6695949f2130c6e34ca5fff08f3beefcb9b4a98446fe9f' 
  AND token = 'u+sWiVMBM+mBs8DLWV7fEj0uUJ4nCwS0XOLlLfZzqQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}