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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48a77babe1cd16d84286d699dc15bdbe082829f0c7faa4136407a19375f1092' 
  AND token = 'GZF6qWimY5dxyYzIOKdwkPeohYI8UNfiSIuClg6xb5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}