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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35184c879dba817b59039485a6e5527613ba1b8f54bcab3046f55dddbe3d083e' 
  AND token = 'pPF8Cd2QG68HWBF5KSx8zel042LfsAZ0nVijWMQQqSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}