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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef8c623eec2249af82ed4251b705177b41b6b98e957d144f8ec1c8839d3943c' 
  AND token = 'vmdsTLDPhmF5MMVBxXGxiV+KUgRE3g22ONlexBT9y1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}