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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a81bb3a8b9dd39570ebe5f5fc1c1e33eb493a302070619d08abadf5e0b373dc' 
  AND token = '+XsLy8vXh3EzomaDfZRgezjTMAZQABVXHRm47Mp92Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}