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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae97298a9cb8aac17736cb9448c45ec869c3c202579cbee8087c6bbeea4ae4c0' 
  AND token = 'r+8H2GfxRU7KVReqYA0x5lKnXpibWlR0Ex0P+kIYZ1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}