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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8221e43dff0b2f1ec8d8b4f3dfce12fac260cbee4f4ef83cf94c01684ea7fd' 
  AND token = 'w3//GhluEaN1Kggmyd9z+SBTIYraTiBadYwwtnbbc4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}