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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f9e78ad0487e9c1ec52723328cc5c45ad554eaac5e96b7644fbe21923defc9' 
  AND token = 'Yxq5HzIJPklWSOa3R0cYwPkj3uu6uvD3pa4PCyoeh3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}