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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0c3d7b10d7ef0873c5b1ffdc75b4117710fe0940dcdf73dedc5ae7e36194ff' 
  AND token = 'zo1uFDqlQ3ElsJd3/K9kQH9VenAjK0fA2U7ktRsvSAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}