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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dca7040296b1c2af611d13593cbb2bd950d620ba995b658ef9b7e5e25c3fd47' 
  AND token = 'SH0lIPZSSKheh8yb3TuNT2QvyYMvS4/ZEYEYWf6UI+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}