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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7f80c4783d0ad906c5d4cc022333818f522f3a38d835828138fe051dbc9e7c' 
  AND token = 'jwvvZWx63Rp33Eg+IUA+ctoVOXbvopcVi+g3LT9M1qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}