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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6d6fbfb1073ded65e31fd7074c5fc5bfd6cdfd5da9422bdb415f56def778e8' 
  AND token = 'acc1Tky0IY2EhGCs2U7r+nT7GjVfYvhvdNjpuT6rVlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}