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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16565d66514b8cd01a1dee048c67420f7f2aa0c77d8ad2a14db6ca99443af9c3' 
  AND token = '4tXwsRdGr9Q7nqCP6/1XlVLbOJxXX+8Mgk2a2IYmW+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}