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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d33547e8532bd77d6fb894e5fa7584a781ac12af6b2859dff26de30f5af16b' 
  AND token = '7fCy2jpr275a4DnD+ZJaXKyWOXpxccrcAAgEGbAHJaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}