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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cea5263ad66c31e407d204f65d91beae2390e01b26888977025715e37c4eb0' 
  AND token = 'PjiBl7OdGHchRpsP0cTN/QZJbRxuzyaUvcvq3IrvuQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}