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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a77eec8085168b2aff9e55f9f2aeeca0086699b36993ce3db99f8655d9b7b2' 
  AND token = '9RPfBC9E+ccrIGiGMoG7gxDzUze54xAppTbLhyzYCRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}