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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9ed38702f5a6e65ee10a5aca03fb284449f83419b6c2616211f98a16ac6847' 
  AND token = 'RMzkn8HC3WbwLyUxPUpBiunZSWTeYCoH64enU6TaF2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}